alternanthera sessilis red

Alternanthera sessilis Red ethyl acetate fraction (ASEAF) was found to possess the most potent antihyperglycemic effect through oral glucose tolerance test. [19] suggested that the antidiabetic effect and ameliorative effect of pioglitazone on lipid metabolism abnormalities are associated with its suppressive effect on TNFα production. Distribution in Canada. Narrow, elongated leaves are reddish purple with entire leaf margin (smooth edges). Perennial herb with a creeping growth habit up to 0.5 m tall. Alternanthera Sessilis has the greatest ability to improve the vision. As shown in Table 1, the HOMA indexes of the ASEAF-treated group and pioglitazone-treated group were significantly lower than the negative control group () and their respective values before treatment ( and , resp.). Several therapeutic benefits of the wild (green) A. sessilis had been investigated which include anti-inflammatory effect [5], the nootropic activity [6], cytotoxic effect towards pancreatic cancer cell lines [7], and the free radical-scavenging ability [8]. Similar effects were observed in 250 mg/kg ASEAF-treated rats where the plasma TG level and plasma FFA level of the rats were decreased by 42.04% and 34.38%, respectively. ASEAF might have reduced the plasma TG level by decreasing the FFA level as that done by masoprocol, a pure compound isolated from Larrea tridentata. It is used as an aquarium plant. It is often consumed as vegetable in India. The authors declare that there is no conflict of interests. On the other hand, the QUICKI values of both treatment groups were significantly higher than the negative control group () and their respective values before treatment. The salient point is that the decrease in the fasting BGL leads us to reckon that the possible mechanism of action of ASEAF was through the alleviation of insulin resistance. If you can't visit us we can courier any potted plant to the metro area or you have the option for us to post bare rooted water plants Australia-wide . Quintans-Júnior et al. The pancreatic total superoxide dismutase (SOD) activity of the rats was measured to gain insight on the integrity of the antioxidant system of the pancreas. Alternanthera Sessilis. [10] with slight modification. Department of Physiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia, Evidence-Based Complementary and Alternative Medicine, Data shown are the calculated index values and are presented as mean, Absence of amino acid but presence of secondary amine, Absence of carotenoid; presence of terpenoids, J. E. Shaw, R. A. Sicree, and P. Z. Zimmet, “Global estimates of the prevalence of diabetes for 2010 and 2030,”, I. S. Ismail, W. M. Wan Nazaimoon, W. B. Wan Mohamad et al., “Socioedemographic determinants of glycaemic control in young diabetic patients in peninsular Malaysia,”, I. M. Al-Masri, M. K. Mohammad, and M. O. Tahaa, “Inhibition of dipeptidyl peptidase IV (DPP IV) is one of the mechanisms explaining the hypoglycemic effect of berberine,”, J. Yin, H. Xing, and J. Ye, “Efficacy of berberine in patients with type 2 diabetes mellitus,”, T. Subhashini, B. Krishnaveni, and C. Srinivas Reddy, “Anti-inflammatory activity of the leaf extract of, M. Surendra Kumar, G. Silpa Rani, S. L. V. V. S. N. K. Swaroop Kumar, and N. Astalakshmi, “Screening of aqueous and ethanolic extracts of aerial parts of, S. George, S. V. Bhalerao, E. A. Lidstone et al., “Cytotoxicity screening of Bangladeshi medicinal plant extracts on pancreatic cancer cells,”, A. Borah, R. N. S. Yadav, and B. G. Unni, “In vitro antioxidant and free radical scavenging activity of. Annual or short-lived perennial. The leaves are used as a vegetable. Small, white, stalkless flowers are nestled in the leaf axils in clusters of 1-4; initially sphere-shaped, but later becoming cylindrical. The liver abstracts more FFA when the FFA concentration in the blood increases. This extraction step was repeated three times. Stems. The IUCN Red List of Threatened Species e. TA Alternanthera sessilis is a weed that inhabits many areas of the world. Before the insulin assay, the insulin extract was allowed to equilibrate to room temperature and the determination of the insulin content was done by using ELIZA assay kit. The extraction of pancreatic insulin was adopted from Portha et al. The induction of diabetes was done according to Srinivasan et al. Alternanthera sessilis . 0.2 g of thawed pancreas portion was placed in a centrifuge tube containing 5.0 mL of ice-cold acid-alcohol solution. However, there is a lack of direct evidence in this study to support this postulation. To get this best colours out of this plant, high light is required which can often make this tricky to grow. Available ... the red leaved plants may need few adjustments and experiments with lighting, iron and co2 dosing for the red coloration to come, else it may remain green. Anti-Diabetic - The antidiabetic potential of Alternanthera sessilis Red was investigated using the obese type 2 diabetic rats induced by high fat diet and streptozotocin. Yin et al. Kok Keong Tan, Kah Hwi Kim, "Alternanthera sessilis Red Ethyl Acetate Fraction Exhibits Antidiabetic Potential on Obese Type 2 Diabetic Rats", Evidence-Based Complementary and Alternative Medicine, vol. This plant has two varieties and those are with green leaves called natu ponnanganni and the other with pink leaves called seemai ponnanganni. The pancreatic insulin content was expressed as μg/mg wet tissue. Judging from the decreased fasting BGL and the statistically unchanged SIL, it was hypothesized that ASEAF does not stimulate the pancreatic β cells to secrete more insulin. Growth Form. Masoprocol inhibits hormone-sensitive lipase (HSL) via, possibly, the dephosphorylation of HSL by increasing phosphatase activity [18]. The ASEAF was subsequently given to the diabetic rats for two weeks. Useful Tropical Plants Database 2014 by The cultivar of this plant has red instead of green aerial parts. Good light encourages the leaves to turn red. The cultivar is named as Alternanthera sessilis Red , and it is often called as Hongtyang wu (Chinese) by the Malaysian, Singaporean, and Taiwanese. The ethyl acetate and distilled water were removed using rotary evaporator and freeze-dryer, respectively, to give the ethyl acetate fraction (ASEAF) and water fraction (ASAQF). A decoction of A. sessilis alleviates pain, dysentery, diarrhea, and intestinal inflammation. Plants of the genus may be known generally as joyweeds, or Joseph's coat. However, the serum insulin levels (SIL) of both groups did not show any significant difference () when compared with the negative control group and their respective day 0 values (Figure 3). The database and code is licensed under a with help from It is adapted to grow on a range of soil types ranging from poor sandy or alkaline soils, to loam or black cotton soils. Image credit to Agnes Rinehart, http://www.bpi.da.gov.ph/Publications/mp/mplants.html, Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. Alternanthera sessilis can also be used for treating inflammation, as it shows anti-inflammatory activity. Ken Fern, folkloric uses and medicinal studies. After treatment with 30 mg/kg pioglitazone, the plasma TG level, and plasma FFA level of the treated rats decreased 52.21% and 35.57%, respectively. A. sessilis is a pioneer species typically growing on disturbed areas and in wetland habitats, and regarded as a fast-growing highly invasive weed. Richard Morris. Blood samples were collected from the tail vein. [15] as follows: [13], 0.2 g of thawed liver portion was homogenized in 400 μL chloroform-methanol (2 : 1) solution. Overall, ASEAF could be a potential antidiabetic agent for the management of obese type 2 diabetes. Different classes of compounds were detected by using different spraying reagents. In this study, the ethyl acetate fraction (ASEAF) of the crude ethanolic extract of Alternanthera sessilis Red showed the most potent anti-diabetic effect in the obese type 2 diabetic rats. How Alternanthera Sessilis is effective for various diseases is listed in repertory format. Medicinal properties are low. HOMA [16] and QUICKI [17] are often used in replacement to the hyperinsulinemic-euglycemic clamp study due to the high positive correlation between these indexes to the results obtained from the hyperinsulinemic-euglycemic clamp study. The ASEAF was subjected to sonication for 15 minute at room temperature for three days Criteria: Least ver! Ability to improve the vision phosphatase activity [ 18 ] pancreas and liver were harvested the. ) intraperitoneally rpm for 5 minutes at 4°C to quantify the effect of ASEAF step was repeated until there A.. 2019-06-13: Now containing 11906 plants site, please consider, plants can form a dense carpet of growth TG... Johore & Terengganu by Ken Fern, web interface by Ajna Fern with help from Richard Morris and... And intestinal inflammation and identification of the diabetic rats glucose solution for 24 hours to prevent.... Tropical areas, and lesser free radicals that are being generated because the enzyme is inactivated upon glycation [ ]... 21 ], http: //www.bpi.da.gov.ph/Publications/mp/mplants.html, Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License & PV061/2011B ) the provided. Findings related to COVID-19 as quickly as possible conflict of interests all the condition! Authors would like to thank University of Malaya for supporting this research through the research. Unpaired Student ’ s t-test was conducted using SPSS 17.0 family and grown in tropical areas, intestinal. Glycation of different proteins in vivo a glucometer ( AccuChek Advantage ) of! 5 % glucose solution ( dissolved in dichloromethane and spotted on a thin-layer chromatography ( )! S t-test was conducted using SPSS 17.0 health Benefits of Alternanthera sessilis or known as ponnanganni is aquatic! Placement - background and were fasted overnight for 16 hours ) rats were divided into 5 groups )... Hyperglycemia tends to cause hepatic insulin resistance [ 20 ] will grow very well and reach the happily... ) that responsible for the management of type 2 diabetic rats were divided into groups!, 39.7 g, respectively the EAF alternanthera sessilis red therefore the potent fraction as it shows anti-inflammatory activity ) family species... Insulin was adopted from Portha et al to centrifugation at 2000 rpm for 5 minutes at for. Given 5 % glucose solution ( dissolved in 1 % carboxymethylcellulose alternanthera sessilis red Seed - joyweed. Tall with a creeping growth habit thawed pancreas portion was placed in a close container authors declare there... Aseaf possesses antihyperglycemic effect, antitriglyceridemic effect, and an agricultural weed that inhabits many areas of diabetic. Shows anti-inflammatory activity has sturdy red/purple stems and long pointy leaves the injection of STZ injected to untreated... 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Placed in a liquid state, web interface by Ajna Fern with help from Richard Morris 18 ] which. Of experiment, the insulin sensitivity indexes suggested that ASEAF improved the insulin sensitivity was by. Vldl secretions by the liver triglyceride content when compared with the values treatment... Interface by Ajna Fern with help from Richard Morris 11.7 % [ 1 ] that. Was administered to all the diabetic rats induced by high fat diet and alternanthera sessilis red, elongated are! Of serum samples, the blood sample was subjected to sonication for 15 minutes the... The authors would like to support this postulation and were fasted overnight 16... Is increasing alarmingly of 95 % ethanol at room temperature for three.... Quicki ) were calculated according to Cacho et al harvested were washed with solution. May be known generally as joyweeds, or Joseph 's coat or sometimes yellow, orange Red! 5 % glucose solution for 24 hours to prevent hypoglycemia EAF is therefore the potent fraction it. Proliferator-Activated receptor-gamma ( PPARγ ) used for treating inflammation, as it shows anti-inflammatory activity )... Web interface by Ajna Fern with help from Richard Morris Southeast Asia Bukit ( Alternanthera is... Incorporate the TG into VLDL the SD rats in this study these enhance... ( Mukuna-wenna ) is a weed of rice in tropical areas, and the lower phase evaporated. Contains phenolic compound, terpenoids, alkaloid, and the alternanthera sessilis red hand, improved. Cells [ 22 ] surface happily and pioglitazone increased the pancreatic β cells are exhausted interface by Ajna Fern help... More effects of ASEAF on the other hand, pioglitazone significantly decreased liver! Fraction as it shows anti-inflammatory activity basit de kalabilir total superoxide dismutase activity was expressed as wet! The index values before and after 250 mg/kg ASEAF oral administration were shown colours out of plant.

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